Stevens-Johnson Syndrome (SJS) Update: What Doctors Have Discovered in the Past 5 Years

Little was known about Stevens-Johnson syndrome in the past. However, medical technology has improved and what has been discovered about SJS in the past five years has “connected the dots” for doctors and Stevens-Johnson syndrome attorneys who represent patients who have contracted it – many by simply taking over-the-counter drugs found in most U.S. households. Unfortunately, manufacturers have been negligent in providing adequate warning.

SJS is not a “mysterious” condition

Recent research conducted by geneticists shows that patients with a certain genetic make-up are predisposed to SJS. In fact, scientists now have identified specific genotypes which will allow them to predict which groups of people may be at higher risk for developing SJS when taking certain drugs because their genetic make-up changes the way their body metabolizes the drugs.

SJS may have been a “mysterious” condition in the past, but thanks to current research, it is becoming clearer that certain genetic factors, when combined with certain drugs, creates a high risk of developing this serious condition. The factors that cause SJS are not so mysterious any more.

Manufacturers knew of risks, but failed to warn

While scientists have made new discoveries in the past 10 years involving the link between genetics coupled with certain drugs and SJS, pharmaceutical manufacturers have not kept pace by adequately warning consumers about this link and the potential risks of developing SJS. In nearly all instances, the manufacturers’ labels are completely void of this information, which is critically needed by the prescribing physician in order to identify which patients are at risk and to closely monitor them while they are using an identified drug.

Some Manufacturers waited too long to warn patients

While some manufacturers have completely failed to warn patients, others have done so, but only after waiting an excessively long time. In 2005, scientists in Asia discovered a connection between the drug carbamazepine, an anticonvulsant and mood stabilizing drug, and SJS. The drug seemed to act as a triggering mechanism for the condition. Yet it wasn’t until December of 2008 – a 3-4 year period – that the label was changed, a 3-year period in which some people most certainly developed and/or died from SJS.

If you’ve contracted SJS, contact an experienced Stevens-Johnson syndrome attorney to discuss your situation, evaluate your legal options and determine the types of SJS damages for which you may be entitled.

FreeAdvice acknowledges the attorneys and experts at Advocate Law Group, PC and Aylstock, Witkin, Kreis & Overholtz, PLLC for their contributions to this article.

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